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Comparison of brain network indicators between mild cognitive impairment and normal cognitive function in elderly patients undergoing transurethral resection of the prostate under anesthesia: a cross-sectional study

Comparison of brain network indicators between mild cognitive impairment and normal cognitive function in elderly patients undergoing transurethral resection of the prostate under anesthesia: a cross-sectional study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118540
Enrollment
Unknown
Registered
2026-02-06
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 65-80 years; 2. ASA classification I-II; 3. Undergoing transurethral resection of the prostate; 4. Education level >= 9 years (junior high school or above); 5. Montreal Cognitive Assessment (MoCA) <= 24 points.

Exclusion criteria

Exclusion criteria: 1. Preoperative pain score (NRS) >= 4; 2. Preoperative Mini-Mental State Examination (MMSE) <= 23; 3. Alcohol abuse; 4. Epilepsy; 5. Parkinson's disease; 6. History of cerebrovascular disease; 7. History of stroke; 8. History of craniotomy; 9. Renal dysfunction (creatinine clearance < 60 ml/min); 10. Liver dysfunction (Child-Pugh class B or C); 11. Use of opioids, clozapine, olanzapine, or risperidone within 1 month; 12. Use of ketamine, midazolam, or dexmedetomidine within 1 month; 13. Pacemaker implantation; 14. Patients with writing or hearing impairments; 15. Sleep apnea syndrome; 16. Refusal to participate in the study.

Design outcomes

Primary

MeasureTime frame
global efficiency of a band ;

Secondary

MeasureTime frame
Global efficiency of d ? and ß band;brain network characteristic path length of d ? a and ß band;Clustering coefficient of d ? a and ß band;

Countries

China

Contacts

Public ContactZongyang Qu

Beijing Hospital

qzyqzy007@sina.com+86 136 9921 8965

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026