Osteoporosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >=50 years, diagnosed with osteoporosis (DXA T-score <= -2.5 or history of fragility fracture); 2. At least one bone density test has been performed at our hospital; 3. Patients who are mentally alert and able to cooperate with functional tests such as gait speed and grip strength; 4. Participants voluntarily agree to participate in this clinical study and have signed a written informed consent form; 5. Willing to receive anti-osteoporosis medication treatment; 6. Willing to complete routine clinical examinations, imaging studies, and biochemical tests; 7. Willing to attend long-term outpatient follow-up in our department;
Exclusion criteria
Exclusion criteria: 1. Secondary osteoporosis caused by malignant tumors; 2. Presence of activ. infections, such as human immunodeficiency virus (HIV) and active tuberculosis; 3. Other severe systemic diseases that may affect the research results: rheumatoid polymyalgia, polymyositis, and fibromyalgia, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes of bone mineral density (BMD); | — |
Secondary
| Measure | Time frame |
|---|---|
| Muscle-related indicators (muscle mass, muscle strength);Internal Capability Assessment;Clinical outcomes and complications;Serum-related indicators; | — |
Countries
China
Contacts
The University of Hong Kong-Shenzhen Hospital