Peptic ulcer bleeding (Forrest Ia–IIa) requiring emergency endoscopic hemostasis
Conditions
Interventions
Hemostatic Powder plus Standard Endoscopic Therapy Group:Microporous polysaccharide hemostatic powder combined with standard endoscopic hemostatic therapy
Standard Endoscopic Therapy Group:Standard endoscopic hemostatic therapy
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18–80 years. 2. Patients undergoing standard endoscopic therapy for the first time for peptic ulcer bleeding (Forrest Ia-IIa); 3. Voluntarily agree to participate and sign the written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Failure to achieve hemostasis with standard endoscopic therapy. 2. Multiple peptic ulcer bleeding; 3. Coagulation disorders (APTT > 1.5× normal or INR > 2.5) or thrombocytopenia (PLT < 100×10?/L). 4. Concomitant esophageal variceal bleeding. 5. Inability to discontinue anticoagulant or antiplatelet therapy. 6. Severe comorbidities involving the heart, lungs, liver, or kidneys. 7. Concomitant malignant tumors. 8. History of abdominal surgery. 9. Pregnant or breastfeeding women. 10. Any other condition deemed unsuitable for participation by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rebleeding rate within 3 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause mortality within 30 days;Length of hospital stay;Incidence of adverse events;Rebleeding rate within 30 days;Transfusion rate; | — |
Countries
China
Contacts
Public ContactXu Shu
The First Affiliated Hospital of Nanchang University
Outcome results
None listed