Ischemic stroke
Conditions
Interventions
Intervention group:?-3 polyunsaturated fatty acids (?-3 PUFAs)
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Multimodal neuroimaging, including diffusion tensor imaging (DTI) sequences, will be performed within 2 weeks after stroke onset and again at 6 months post-onset. 2. Able to cooperate with and complete a comprehensive cognitive function assessment battery. 3. Able to comply with long-term clinical and neuroimaging follow-up.
Exclusion criteria
Exclusion criteria: 1. Individuals with pre-existing cognitive impairment prior to stroke. 2. Individuals who are unable to tolerate or complete brain MRI examinations, including DTI sequences. 3. Individuals whose imaging data are compromised by severe head motion–related artifacts, precluding subsequent image post-processing and analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-stroke cognitive impairment at 6 months; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive impairment after stroke at 6 months;Atherosclerotic Cardiovascular Disease (ASCVD) events within 6 months; | — |
Countries
China
Contacts
Public ContactSheng Zhang
Zhejiang Provincial People's Hospital
Outcome results
None listed