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Neural Mechanisms of Subgenual Anterior Cingulate Cortex-Targeted Personalized Transcranial Magnetic Stimulation for Treating Insomnia

Neural Mechanisms of Subgenual Anterior Cingulate Cortex-Targeted Personalized Transcranial Magnetic Stimulation for Treating Insomnia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118502
Enrollment
Unknown
Registered
2026-02-06
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Individuals experience difficulty falling asleep

Interventions

group 2:Conventional "5 cm" Rule
group 1:sgACC-mPFC FC-Guided Personalized TMS Targeting Group

Sponsors

The Affiliated Hospital of Hangzhou Normal University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18–65 years; 2. Meets the "Chinese Guidelines for the Diagnosis and Treatment of Insomnia," clinically diagnosed with CID; 3. Course of illness over 13 weeks; 4. PSQI >=11.

Exclusion criteria

Exclusion criteria: 1. History of brain surgery or head trauma; 2. History of alcohol, drug, or psychoactive substance abuse; 3. Family history of mental illness or history of other psychiatric disorders; 4. Insomnia caused by other sleep disorders, such as sleep apnea syndrome, restless legs syndrome, or periodic leg movements; 5. Pregnant or breastfeeding women; 6. Contraindications for MRI or TMS; 7. Altered consciousness or concurrent severe heart, liver, or kidney dysfunction.

Design outcomes

Primary

MeasureTime frame
Sleep Quality;

Secondary

MeasureTime frame
Regional Brain Activity;Adverse Effects of TMS;Cognitive Function;Insomnia;

Countries

China

Contacts

Public ContactZhao Na

The Affiliated Hospital of Hangzhou Normal University

20237020@hznu.edu.cn+86 571 28867717

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026