Mechanistic study of Rho-Rock signaling in the establishment of early embryonic polarity

Study on the regulatory role and mechanism of the Rho-Rock signaling pathway in polarity establishment and blastocyst formation during human early embryonic development

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2600118499

Enrollment

Unknown

Registered

2026-02-06

Start date

2026-02-08

Completion date

Unknown

Last updated

2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blastocyst formation failure

Interventions

ROCK inhibitor-treated group:none

Control:none

RHO inhibitor-treated group:none

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Select normal cleavage stage embryos that patients voluntarily give up and agree to be used for scientific research.

Exclusion criteria

Exclusion criteria: NA

Design outcomes

Primary

Measure	Time frame
Blastocyst formation rate and the expression of polarity markers;	—

Countries

China

Contacts

Public ContactMing Zeng

The Third Affiliated Hospital of Guangzhou Medical University

zengming700@163.com+86 20 8129 2957

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026