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A machine learning-driven clinical prediction model for rebound pain following nerve block

A machine learning-driven clinical prediction model for rebound pain following nerve block

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118491
Enrollment
Unknown
Registered
2026-02-06
Start date
2026-02-10
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rebound pain after peripheral nerve block

Interventions

bservational group:None

Sponsors

Xiangyang Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients admitted to Xiangyang Central Hospital who are undergoing upper limb surgery for the first time, aged >= 18 years, with ASA physical status I-III, and scheduled to undergo unilateral upper limb surgery (involving the clavicle, shoulder joint, and below) under brachial plexus block.

Exclusion criteria

Exclusion criteria: 1. Patients with other site surgery; 2. Emergency patients; 3. Peripheral neuropathy, preoperative operative upper limb with nerve injury; 4. Previous axillary surgery on the operative side; 5. Multiple operations on the upper limb of the surgical side (>1); 6. Patients with contraindications of local anesthesia drug allergy and postoperative analgesics (such as NSAID and paracetamol); 7. Pregnant patients; 8. Patients with diabetes and vascular diseases; 9. Long-term use of opioids, antipsychotics, antidepressants; 10. Injection site infection, acute porphyria or kidney disease requiring dialysis; 11. Patients with contraindications to regional anesthesia, general anesthesia and nerve block insufficiency to assist general anesthesia or change general anesthesia; 12. Patients with chronic pain syndrome; 13. Patients who are unable to understand the perioperative questionnaire (language problems or cognitive impairments); 14. Have participated in similar studies in the past three months.

Design outcomes

Primary

MeasureTime frame
resting pain, average daily pain, most severe pain, and night pain scores;Area under the ROC curve;sensitivity;specificity;

Secondary

MeasureTime frame
NRS scores at 1,2 and 3 days after surgery(resting pain, average daily pain, most severe pain, and night pain scores);dosage of postoperative analgesics(opiods, NSAIDS);quality of sleep;postoperative side effects(headache, dizziness, nausea, vomiting);anxiety scores;

Countries

China

Contacts

Public ContactXingrui Gong

Xiangyang Central Hospital

40415311@qq.com+86 710 3522567

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026