This study does not target a single specific disease, but focuses on all types of severe adverse clinical events caused by medications. Commonly affected organ systems include, but are not limited to: Skin and Appendage Damage: e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis. Systemic Damage: e.g., anaphylactic shock, drug fever. Hepatobiliary System Damage: e.g., severe drug-i
Conditions
Interventions
Observation group:None
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Occurrence of a drug adverse event meeting the criteria for a Severe Adverse Drug Reaction (ADR) during hospitalization at our institution. 2.Availability of complete medical records allowing for the retrieval of detailed information regarding the ADR diagnosis, management, and clinical outcome.
Exclusion criteria
Exclusion criteria: 1.The ADR event occurred before admission or after discharge. 2.The ADR event was a mild reaction (e.g., Grade 1 nausea, headache) not requiring medical intervention. 3.Severely incomplete medical records that preclude a reliable causality assessment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and Profile of Severe ADRs; | — |
Countries
China
Contacts
Public ContactWei-Jing Gong
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed