Herpes Zoster, Postherpetic Neuralgia
Conditions
Interventions
Cross-sectional study group (pain duration 12 months):None
Cross-sectional study group (healthy control):None
Longitudinal study group:None
Sponsors
Renji Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for Patients with Herpes Zoster or Postherpetic Neuralgia: 1. Age 40–70 years (55–70 years in Study II); 2. Diagnosis of herpes zoster confirmed by clinical examination combined with viral culture and immunofluorescence staining, or a definite history of herpes zoster with a diagnosis of postherpetic neuralgia confirmed by physical examination; 3. No psychiatric disorders or relevant medical history; 4. No recent use of psychotropic medications; 5. Normal cognitive function and able to communicate and perform experimental tasks; 6. Written informed consent provided by the subject. Inclusion Criteria for Healthy Subjects: 1. Age 40–70 years; 2. No neurological or psychiatric disorders or relevant medical history; 3. No recent use of psychotropic medications or medications that may affect the nervous system; 4. Normal cognitive function and able to communicate and perform experimental tasks; 5. Written informed consent provided by the subject.
Exclusion criteria
Exclusion criteria: 1. Severe cognitive and communication impairments that prevent cooperation; 2. Functional impairment or failure of major organs, including the heart, lungs, liver, and kidneys; 3. Failure to meet the requirements for scalp electroencephalography recording, including but not limited to damaged scalp skin, partial absence of brain tissue, cranial defects, or intracranial metal implants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment(MoCA) Beijing Version; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS Pain Score Scale;Douleur Neuropathique 4 questions,(DN4);electroencephalogram (EEG);Pittsburgh Sleep Quality Index (PSQI);Patient Health Questionnaire-9;Generalized Anxiety Disorder-7; | — |
Countries
China
Contacts
Public ContactHuichun Luo
Renji Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed