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Study on Brain Function Activation and Functional Connectivity Differences in Masticatory Movements of Adolescents with Skeletal Class II Based on fNIRS

Study on Brain Function Activation and Functional Connectivity Differences in Masticatory Movements of Adolescents with Skeletal Class II Based on fNIRS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118392
Enrollment
Unknown
Registered
2026-02-04
Start date
2026-02-04
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malocclusion

Interventions

Adolescents with skeletal Class II mandibular retrognathism:None
People with normal Class I skeletal occlusion:None

Sponsors

Weifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria Experimental Group (Skeletal Class II) Lateral cephalometric radiograph shows: 1. Cervical vertebral maturation assessed by modified method indicates CS2~3 stage. 2. ANB >= 5° (Skeletal Class II), BMI 18.5-24 kg/m^². 3. Coben analysis shows mandibular retrognathia. Clinical indicators: 1. No systemic or genetic diseases affecting craniofacial development. 2. No prior orthodontic treatment history. 3. No obvious symptoms of temporomandibular joint disorders (pain, clicking, limited mouth opening). For the control group, aside from 1° <= ANB <= 5° (Skeletal Class I), all other criteria are the same as the experimental group.

Exclusion criteria

Exclusion criteria: 1. The improved cervical vertebra bone age shows an inappropriate age. It does not meet the criteria for skeletal Class II malocclusion and there are other severe maxillofacial disorders.

Design outcomes

Primary

MeasureTime frame
ANB;

Countries

China

Contacts

Public ContactFanghong Yang

Weifang People's Hospital

rmyyyfh@sdsmu.edu.cn+86 536 819 2340

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026