Skip to content

Study on the therapeutic effect and anti-inflammatory/oxidative stress effects of modified Dahuangling Pi Formula in delaying the transformation of acute kidney injury into chronic kidney disease

Study on the therapeutic effect and anti-inflammatory/oxidative stress effects of modified Dahuangling Pi Formula in delaying the transformation of acute kidney injury into chronic kidney disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118385
Enrollment
Unknown
Registered
2026-02-04
Start date
2023-07-21
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury

Interventions

Control group:Routine basic treatment: control diet (low salt, low fat, high-quality low protein), lower blood pressure, correct heart failure, correct insufficient blood volume, control infection, co
Trial group:Basic treatment+treatment with Dahuangling Pi Formula

Sponsors

Yueyang Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Complies with the KDIGO standards recommended by AKI in the 2012 KDIGO Guidelines for Improving Global Kidney Disease Prognosis; Or meet the diagnostic criteria for patients with acute kidney injury based on chronic kidney disease (AonC); 2. Age >= 18 years and <= 75 years old, regardless of gender; 3. The patient agrees and has signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Having cognitive impairment or mental illness that prevents cooperation; 2. Individuals with severe functional abnormalities in the heart, liver, kidneys, and hematopoietic system; 3. Individuals who are allergic to the drugs used in our research group; 4. Pregnant or lactating women; 5. Individuals who have participated or are currently participating in other clinical trials within the first month prior to enrollment.

Design outcomes

Primary

MeasureTime frame
Serum creatinine;Renal function, estimated glomerular filtration rate (eGFR);

Secondary

MeasureTime frame
24-hour urine protein quantification;

Countries

China

Contacts

Public ContactXie Gangling

Yueyang Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Shanghai University of Traditional Chinese Medicine

xguangliang@126.com+86 189 1707 9176

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026