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Comparison of the Efficacy of Different Temporal Orders of Combined Central and Peripheral Repetitive Magnetic Stimulation on Upper Limb Motor Dysfunction after Stroke

Comparison of the Efficacy of Different Temporal Orders of Combined Central and Peripheral Repetitive Magnetic Stimulation on Upper Limb Motor Dysfunction after Stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118382
Enrollment
Unknown
Registered
2026-02-04
Start date
2026-02-07
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke upper limb motor dysfunction

Interventions

Sequential Group 1 (rTMS followed by rPMS):Combined intervention of repetitive transcranial magnetic stimulation (rTMS) followed by repetitive peripheral magnetic stimulation (rPMS)
Sequential Group 2 (rPMS followed by rTMS):Combined intervention of repetitive peripheral magnetic stimulation (rPMS) followed by repetitive transcranial magnetic stimulation (rTMS)
Synchronous Intervention Group:Synchronous combined intervention of repetitive transcranial magnetic stimulation (rTMS) and repetitive peripheral magnetic stimulation (rPMS)

Sponsors

Beijing Bo'ai Hospital, China Rehabilitation Research Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. First onset of stroke with stable condition; 2. Aged 18-80 years; 3. Presence of unilateral upper limb motor dysfunction, with Brunnstrom stage ?-?; 4. Stable vital signs, clear consciousness, and ability to understand and cooperate with simple instructions; 5. Signed informed consent form by the patient or their legal guardian.

Exclusion criteria

Exclusion criteria: 1. Other intracranial lesions (such as tumors, trauma, etc.); 2. Severe cognitive impairment (MoCA score < 15 points) or sensory aphasia; 3. Complicated with severe diseases of major organs such as the heart, liver, and kidneys; 4. Metal implants in the head, cardiac pacemaker, or other contraindications to rTMS; 5. Skin damage or infection of the affected upper limb, making them unsuitable for rPMS treatment.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Assessment of Motor Function - Upper Extremity (FMA-UE);—

Secondary

MeasureTime frame
Functional Near-Infrared Spectroscopy (fNIRS); Modified Barthel Index (MBI);Simple Test for Evaluating Hand Function (STEF); Muscle Tone Tester;Fugl-Meyer Sensory Function Assessment - Upper Extremity (FMA-S);Montreal Cognitive Assessment(MoCA); Modified Ashworth Scale (MAS);Active Range of Motion of Wrist Dorsiflexion (AROM);—

Countries

China

Contacts

Public ContactHuang Fubiao

Beijing Bo'ai Hospital, China Rehabilitation Research Center

huangfubiao123@126.com+86 158 1031 1072

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026