Sciatic nerve pain
Conditions
Interventions
Same envelope frequency stimulation groups:tTIS stimulation (Continuous alternating current stimulation, carrier frequency: 2000Hz, envelope frequency ?f = 0Hz, current intensity: 2mA, stimulation tim
different envelope frequency stimulation groups:tTIS stimulation (Continuous alternating current stimulation, carrier frequency: 2000Hz, envelope frequency ?f = 20Hz, current intensity: 2mA, stimulati
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1: The age range is from 18 to 60 years old. There is no gender restriction. Participants must be able to clearly describe their symptoms and cooperate to complete the follow-up. 2: Meets the diagnostic criteria for sciatica: radiating pain along the course of the sciatic nerve (from the lower back to the buttocks, the posterior side of the thigh, the outer side of the lower leg, and the foot), often accompanied by numbness or weakness. 3: Physical examination supports the diagnosis: The straight leg raising test (SLRT) is positive (with an elevation angle of = 4 grade, avoiding severe functional impairment affecting the assessment). 4: Imaging examinations (lumbar MRI/CT) indicated lumbar intervertebral disc protrusion/ protrusion, and the protruded segment was consistent with the location of clinical symptoms and signs. 5: Within one week before enrollment, the participant had not used non-steroidal anti-inflammatory drugs (NSAIDs), muscle relaxants, or glucocorticoids, or had discontinued the use of these drugs but still had unsatisfactory symptoms (to avoid interference from the drugs on the efficacy assessment). 6: Voluntarily sign the informed consent form, commit to following the experimental protocol, and cooperate in completing the treatment and follow-up (such as regular check-ups and filling out pain assessment scales).
Exclusion criteria
Exclusion criteria: 1: Not applicable to patients with sciatica caused by lumbar intervertebral disc protrusion or protrusion. 2: Comorbid severe underlying diseases: such as severe cardiovascular and cerebrovascular diseases (acute stage of coronary heart disease, cerebral infarction), liver and kidney dysfunction (transaminase > 2 times the upper limit of normal value, creatinine > 1.5 times the upper limit of normal value), coagulation disorders (INR > 1.5), or active infections (such as pneumonia, urinary tract infection). 3: Previous relevant surgical history: having undergone lumbar spine surgery (such as discectomy), sciatic nerve block or radiofrequency ablation within 6 months before enrollment, or planning to receive other treatments for sciatica during the experiment. 4: Special populations or contraindications exist: pregnant women, lactating women; allergic to the components of the experimental drug/treatment plan; long-term users of opioid analgesics (such as morphine, oxycodone) or psychotropic drugs (such as antidepressants, sedative-hypnotics); with cognitive impairments or mental disorders (such as depression, schizophrenia) and unable to cooperate with the assessment. 5: Other factors affecting the assessment: Such as having knee osteoarthritis or lower extremity vascular diseases (such as varicose veins, blood clots) that may confuse the cause of lower extremity pain; participating in other clinical trials within 3 months prior to enrollment. 6: Patients with magnetic metal implants in their bodies (such as cardiac pacemakers, implantable cardioverter-defibrillators, certain aneurysm clips, internal magnetic metal foreign bodies, certain cochlear implants, and nerve stimulators) 7: Patients who are unable to undergo MRI examinations (such as those with claustrophobia, those who cannot remain still or follow instructions, those with severe obesity, those with tattoos or permanent makeup).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oswestry Disability Index, ODI; | — |
Countries
China
Contacts
Public ContactYan Luo
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed