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Study on the effect of absorbable collagen membrane on periodontal soft and hard tissue repair and reconstruction in periodontally accelerated osteogenic orthodontics

Study on the effect of absorbable collagen membrane on periodontal soft and hard tissue repair and reconstruction in periodontally accelerated osteogenic orthodontics

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118344
Enrollment
Unknown
Registered
2026-02-04
Start date
2024-01-19
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insufficient alveolar bone volume

Interventions

Membrane group:PAOO + Bone Graft + Absorbable Collagen Membrane
Control group:PAOO + Bone Graft

Sponsors

Beijing Stomatological Hospital, Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18–40 years, regardless of gender; 2. Periodontally healthy, with no active periodontitis or with stable periodontal conditions.

Exclusion criteria

Exclusion criteria: 1. Patients with hypertension whose systolic blood pressure was >200 mmHg or diastolic blood pressure was >115 mmHg within one month prior to surgery; 2. Patients with systemic diseases (e.g., malignant tumors, diabetes, heart failure secondary to heart disease, myocardial infarction within the past six months, angina symptoms within the past six months, congenital heart disease, etc.); 3. Individuals who used non-steroidal anti-inflammatory drugs (NSAIDs), bisphosphonates, or corticosteroids prior to treatment; 4. Patients with uncontrolled periodontal disease, active periodontal infection, or systemic infection; 5. History of surgical treatment or other therapies in the surgical area or adjacent sites; 6. Known allergy to any drugs or materials used during the procedure, or patients with a hypersensitive constitution (atopy); 7. Severe hepatic or renal insufficiency; 8. Patients with bleeding tendencies or coagulation disorders (White Blood Cell count 10 cigarettes/day); 12. Other patients deemed unsuitable for inclusion by the researchers (e.g., failure to meet randomization conditions, history of alcoholism, intravenous drug abuse, etc.).

Design outcomes

Primary

MeasureTime frame
Change in alveolar bone wall thickness;Probing Depth;Bone density;Speed of tooth movement;Periodontal attachment level;

Secondary

MeasureTime frame
Bleeding on Probing;

Countries

China

Contacts

Public ContactYitong Liu

Beijing Stomatological Hospital, Affiliated to Capital Medical University

15010546495@163.com+86 150 1054 6495

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026