Postoperative Pain
Conditions
Interventions
Experimental group:Liposomal Bupivacaine 199.5mg/30ml for Single-Injection Paravertebral Nerve Block
Control group:Ropivacaine 1100mg/350ml for Continuous Paravertebral Block
Sponsors
Huadong Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective thoracoscopic lobectomy at our hospital; 2. Age >= 18 years; 3. American Society of Anesthesiologists (ASA) Physical Status Classification I-III.
Exclusion criteria
Exclusion criteria: 1. BMI < 30 kg/m^2; 2. Combined severe cardiopulmonary insufficiency; 3. Severe allergies to soy, milk, etc.; 4. History of chronic pain due to bone metastasis or other reasons; 5. Infection at the puncture site; 6. Coagulation disorders; 7. Spinal deformities; 8. Individuals with mental illness or cognitive impairment; 9. Those who refuse to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS Score at rest at 48 Hours Postoperation;Postoperative white blood cell count;First remedial analgesia time;Dose of remedial drugs; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS Score at 24 Hours Postoperation;Times of postoperative remedial analgesia;Postoperative Pulmonary Complications (PPCs) Grading Score;Postoperative Nausea and Vomiting (PONV) Score;Patient Postoperative Satisfaction; | — |
Countries
China
Contacts
Public ContactGu Weidong
Huadong Hospital of Fudan University
Outcome results
None listed