Stroke
Conditions
Interventions
cPMd-iM1 PAS group:cPMd-iM1 paired associated stimulation
iM1 high frequency group:high frequency rTMS on iM1
cPMd high frequency group:high frequency rTMS on cPMd
Sponsors
The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. First-ever stroke; 2. Diagnosed by computed tomography or MRI as ischemic or hemorrhagic stroke; 3. Clear consciousness and stable vital signs; 4. Aged 18-80 years, regardless of gender; 5. Between 1 week to 6 months following stroke onset; 6. Unilateral upper limb and hand hemiplegia (Brunnstrom classification as grade I-IV); 7. Right handed according to the Edinburgh Handedness Inventory;
Exclusion criteria
Exclusion criteria: 1. Severe attention impairment; 2, Severe speech, hearing, visual, sensory, intellectual, mental, or cognitive impairments; 3. Severe spasticity or pain; 4. Bone and joint muscle diseases, other severe neurological disorders, malignant tumors, and severe damage to the heart, lungs, liver, or kidneys, etc; 5. From other cities and unable to be followed up; 6. TMS contraindications such as metal implants, magnetic plates, or cardiac pacemakers in the local body 7. Alcohol or drug addiction; 8. Epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Upper Limb Motor Function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Upper limb movement;Barthel Index;MEP;Brunnstrom hemiplegia graded;Manual Muscle ;Modified Ashworth Scale;fMRI assessment indicators; | — |
Countries
China
Contacts
Public ContactLimin Sun
The First Affiliated Hospital of Fujian Medical University
Outcome results
None listed