Infections caused by important clinical pathogens
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Infections caused by clinically significant pathogens, such as Staphylococcus aureus infection, Enterococcus faecalis infection, Enterococcus faecium infection, Escherichia coli infection, Klebsiella pneumoniae infection, Enterobacter cloacae infection, Moraxella catarrhalis infection, Acinetobacter baumannii infection, Pseudomonas aeruginosa infection, Proteus mirabilis infection, and Mycobacterium avium infection, all have corresponding clinical symptoms or imaging support; 2. At least one qualified specimen culture or NGS indicates the corresponding pathogen results; 3. Administer first-line antibacterial drugs and the treatment course is >= 3 days.
Exclusion criteria
Exclusion criteria: 1. Cases with significant lack of clinical data or with low credibility of the data; 2. Cases determined by clinicians as colonization (including cases where the course of the disease indicates colonization or suspected colonization; cases where the patient's symptoms or imaging manifestations improved without taking antibacterial treatment).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of SBP during hospitalization;Discharge outcomes: recovery, symptom relief, difficult to judge (the length of hospital stay was too short to judge), transfer to another hospital without cure, death, automatic discharge but expected death soon, and others;ICU occupancy rate during hospitalization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of SBP 30 days after discharge;The readmission rate within 30 days of discharge and the incidence of readmission due to SBP; | — |
Countries
China
Contacts
West China Hospital of Sichuan University