Idiopathic pulmonary fibrosis
Conditions
Interventions
Gold Standard:Based on the 6-minute walk distance (6MWD)
Index test:Two-dimensional ultrasound and shear wave elastography (SWE) were employed to measure quantitative parameters of the quadriceps muscle, including its thickness (MT), cross-sectional area (C
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 40 years or older. 2. Diagnosis of IPF confirmed according to the official guideline. 3. Provision of signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Disease exacerbation or significant decline in pulmonary function within the past month. 2. Presence of severe cardiovascular or active pulmonary diseases. 3. Any comorbid conditions affecting muscles, neurological disorders, or unilateral limb dominance. 4. Inability to complete the six-minute walk test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AUC;ROC;Positive predictive value;Negative predictive value;Correlation coefficient between ultrasound indices and 6MWD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quadriceps thickness;Quadriceps femoris cross-sectional area;Shear wave modulus value; | — |
Countries
China
Contacts
Public ContactYating Wang
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Outcome results
None listed