Post-Stroke Cognitive Impairment,PSCI
Conditions
Interventions
Cognitive-Motor Dual-Task Training:Patients undergo training combining cognitive tasks with synchronized upper limb motor function intervention. Cognitive tasks are personalized based on initial cogni
Motor training:Standardized exercise rehabilitation including functional upper limb tasks (such as reaching, grasping, and fine manipulation). Training intensity is gradually increased based on patien
Cognitive Training:Patients underwent cognitive training using a computer-assisted cognitive rehabilitation system. The training content was identical to that of the CMDT group, with tasks individuall
Sponsors
Shiyan Taihe Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. 30 years old <= age <= 75 years old, with primary school education or above; 2. The diagnosis of the first stroke is in accordance with the diagnostic points of post-stroke cognitive impairment adopted by the 2021 Expert Consensus on the Management of Post-Stroke Cognitive Impairment; 3. The duration of the disease is from 3 months to 6 months after the stroke, and the vital signs are stable; 4. the presence of upper limb motor dysfunction, with a Fugl-meyer assessment of Upper Extremity (FMA-UE) score between 23 and 55; 5. able to follow experimental instructions; 6. the patient is right-handed and able to remain seated for more than 30 minutes; 7. The patient himself/herself signed or his/her immediate family members signed the informed consent form on his/her behalf.
Exclusion criteria
Exclusion criteria: 1. have a history of severe cognitive impairment or dementia (Mini Mental State Examination, MMSE <18) or previous illnesses other than PSCI that cause cognitive dysfunction; 2. have severe visual, hearing, or speech impairments that prevent them from understanding and cooperating with instructions; 3. Presence of uncontrolled psychiatric mental illness that interferes with cooperation with interventions; 4. Combination of severe motor dysfunction, affecting intervention and assessment; 5. the presence of a comorbid serious cardiac, hepatic, renal or respiratory disorder that does not tolerate rehabilitation; 6. Inappropriate for fNIRS collection due to trauma to the scalp or skull; 7. concurrent participation in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-meyer assessment of Upper Extremity,FMA-UE;Trail Making Test A/B;Brain oxygen saturation;Modified Barthel Index;Event-related potentialP300; | — |
Countries
China
Contacts
Public ContactMingfen Li
Shiyan Taihe Hospital
Outcome results
None listed