Myopia
Conditions
Interventions
Conventional Reverse Curve Height Group:Orthokeratology lenses with conventional reverse curve height
Increased Reverse Curve Height Group:Orthokeratology lenses with increased reverse curve height
Sponsors
West China hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
8 Years to 14 Years
Inclusion criteria
Inclusion criteria: (1) Age 8–14 years, with myopia between -0.50 D and -4.00 D, and astigmatism =0.50 D per year (based on records from the past 12 months); (5) No history of wearing orthokeratology lenses, defocus soft contact lenses, or other contact lenses; (6) Ocular health with no significant ocular diseases (e.g., keratoconus, severe dry eye); (7) Central corneal thickness >=480 µm, and intraocular pressure within the normal range of 10–21 mmHg; (8) Environmental and hygienic conditions suitable for wearing orthokeratology lenses; (9) Ability to understand the mechanism and practical effects of orthokeratology lenses, good compliance, timely and regular follow-up visits, and ability to understand and cooperate with the washout process arranged in this study; (10) The participant and their legal guardian voluntarily agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Anisometropia >1.00 D; (2) Presence of amblyopia in one or both eyes; (3) Strabismus observed after full correction and cover testing (distance/near); (4) Ocular conditions that may affect refractive development or status (e.g., keratoconus, congenital glaucoma, ocular trauma, etc.) or systemic diseases (e.g., diabetes, connective tissue disorders such as Marfan syndrome, Down syndrome, etc.); (5) First-degree relatives (parents, siblings) with congenital night blindness or clinically diagnosed night vision disorders; (6) Known allergy to proparacaine, tetracaine, tropicamide, or cyclopentolate; (7) Abnormal binocular vision or stereopsis; (8) History of ocular surgery; (9) Corneal thickness 21 mmHg or <10 mmHg); (10) Other conditions deemed unsuitable for participation in this study as assessed by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Axial length;Peripheral defocus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual acuity;Subjective refraction;Objective refraction;Corneal Topography;Slit lamp examination;Intraocular pressure;Fundus examination;Specular microscope; | — |
Countries
China
Contacts
Public ContactLongqian Liu
West China Hospital, Sichuan University
Outcome results
None listed