Benign Prostatic Hyperplasia
Conditions
Interventions
Benign prostatic hyperplasia:None
Benign prostatic hyperplasia combined with bladder diverticulum:None
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1.Participants who met the criteria were diagnosed with BPH through clinical examinations and diagnostic tests (such as rectal examination and prostate-specific antigen level testing). Additionally, patients with bladder diverticula confirmed by ultrasound or computed tomography were also included; 2.Voluntary signing of the informed consent form and cooperation in completing urodynamic tests, imaging evaluations, and biological sample collection were required.
Exclusion criteria
Exclusion criteria: 1.Has a history of prostate or bladder surgery or urinary tract tumor; 2.Neurogenic bladder, severe urinary tract infection, stone obstruction (diameter > 1cm), and other diseases that affect urinary tract pressure or hydronephrosis; 3.Severe liver and kidney dysfunction, coagulation disorder; 4.Unable to cooperate with the completion of urinary tract dynamic examination or unable to follow up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detrusor pressure;Bladder filling pressure;Maximum urethral closing pressure;Classification of hydronephrosis;Anteroposterior diameter of the renal pelvis;Thickness of renal parenchyma;Residual urine volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| 8-hydroxydeoxyguanosine;Malonaldehyde;Nitric oxide;Homocysteine;Uric Acid;Prostate volume;International Prostate Symptom Score Attached to Quality of Life Score;Brief Health Status Scale Score;Free prostate specific antigen;Total prostate-specific antigen;Serum creatinine;Urea nitrogen;Glomerular filtration rate;White blood cell count;C-reactive protein; | — |
Countries
China
Contacts
Public ContactYin Shuijing
The Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed