Cervical spondylosis requiring surgical intervention in consecutive two segments
Conditions
Interventions
FA:Anterior Cervical Discectomy and Fusion + Artificial Cervical Disc Replacement
2F:Two-segment Anterior Cervical Discectomy and Fusion
AF:Artificial Cervical Disc Replacement + Anterior Cervical Discectomy and Fusion
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with clinically diagnosed, imaging-confirmed, consecutive two-segment cervical spondylosis; 2.Patients who have undergone standardized conservative treatment but have not responded or whose symptoms have progressively worsened, affecting their daily life and work, and who require intervertebral decompression surgery; 3.The surgical segments are two consecutive segments between C3/4 and C6/7; 4.Be able to fully abide by this agreement psychologically and physically, cooperate with the scheduled treatment plan, fill out forms, and cooperate with follow - up visits; 5.After the patient signs the informed consent, it means that the patient has been informed of and agrees to the implementation and conduct of the relevant aspects of this study;
Exclusion criteria
Exclusion criteria: 1.Patients with a history of cervical spine surgery or adjacent segmental osteoarthritis; 2.Patients with ossification of the posterior longitudinal ligament or cervical spinal stenosis, spinal fractures, severe osteoporosis, or a history of bone metabolic disorders; 3.Patients with obvious instability in the segment requiring surgery (Cobb angle change > 13° in the flexion-extension radiograph, or horizontal displacement of the upper and lower vertebrae > 3 mm); 4.Localized skin infections and ulcers in the neck area, systemic inflammatory diseases, rheumatoid arthritis, uncontrolled diabetes, malignant tumors, active hepatitis, etc. 5.Patients with mental illness or psychological disorders; 6.Patients with poor overall health conditions, severe diseases in vital organs, and inability to tolerate surgery; 7.Known to have infectious diseases such as AIDS, syphilis, etc. 8.Received immunosuppressive therapy daily for more than 1 month in the past 12 months; 9.Allergy to implant materials (PEEK or titanium alloy); 10.Patients with severe obesity or a history of drug abuse; 11.Pregnant women or those planning to become pregnant during the study period; 12.Participating in other studies that may affect the results of this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C2-7 Cobb angle;T1 slope;NDI score;sagittal vertical axis;ROM of adjacent segments;ROM of operated segments; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complications;JOA score;VAS score;fusion rate of fusion segment; | — |
Countries
China
Contacts
Public ContactLiu Hao
West China Hospital of Sichuan University
Outcome results
None listed