Sepsis-associated acute lung injury,Sepsis-associated acute respiratory distress syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age>=18; 2.Patients must be diagnosed with sepsis according to the Sepsis-3 guidelines and concurrently diagnosed with ARDS based on the ESICM guidelines. 3.Patients must have complete medical records and laboratory test data from admission to discharge. 4.The patients and their family members consent and are able to comply with the follow-up and data collection as required by the study.
Exclusion criteria
Exclusion criteria: 1.Patients who died within 24 hours of hospital admission. 2.Age<18; 3.Patients for whom detailed admission and discharge records, as well as other treatment data relevant to this study, cannot be obtained. 4.Patients with immunodeficiency diseases (such as HIV infection, immunosuppressive therapy recipients, solid organ transplant recipients, etc.) or patients receiving long-term immunosuppressive therapy (including corticosteroids, immunosuppressants, etc.) .. 5.Exclude patients who developed systemic inflammatory response syndrome (SIRS) due to non-infectious causes (such as pancreatitis or severe burns). 6.Patients with known underlying or recent medical conditions that could affect SAA1 levels (such as acute coronary syndrome or connective tissue disease). 7.Patients with severe liver disease (such as decompensated cirrhosis and acute liver failure). 8.Patients who are pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SAA1; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver Function Tests;Complete Blood Count;Arterial Blood Gas Analysis;Renal Function Tests;Coagulation Profile; | — |
Countries
China
Contacts
Chongqing Emergency Medical Center