Primary overweight or obesity
Conditions
Interventions
Group of Healthy Children with Normal Weight:none
Group of Children with Overweight and Obesity:None
Sponsors
Xiangya Hospital Central South University
Eligibility
Sex/Gender
All
Age
6 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1.Legal guardians provide consent and sign the informed consent form, and the child (age >=6 years) concurrently provides assent using a child-friendly version of the form; 2.Age between 6 and 18 years (inclusive); 3.Diagnosed with primary overweight or obesity in a specialist clinic, typically corresponding to a BMI >=85th percentile for age and sex, with or without related complications; 4. Healthy group: normal weight (usually corresponds to a BMI between the 5th and 85th percentiles for age and sex)
Exclusion criteria
Exclusion criteria: 1.Presence of secondary causes of obesity, such as endocrine disorders, drug-induced obesity (e.g., due to glucocorticoids, antidepressants like mirtazapine/paroxetine, or antipsychotics like clozapine/olanzapine), syndromic obesity, or monogenic obesity; 2.Diagnosis of Type 1 Diabetes; 3.Coexisting malignancies or severe cardiac, pulmonary, renal, or hepatic dysfunction not attributable to obesity; 4.History of severe cardiovascular or cerebrovascular events within the past 6 months; 5.History of severe gastrointestinal diseases or gastrointestinal surgery within the past 12 months; 6.Current use of medications (other than approved anti-obesity drugs) that are known to affect body weight or energy balance; 7.Concurrent participation in another clinical trial; Health group: Type 1 or Type 2 diabetes, insulin resistance, hyperlipidemia, primary or secondary hypertension, fatty liver, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight;Body mass index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood sugar;Insulin resistance index;Blood lipid;Rate of weight regain; | — |
Countries
China
Contacts
Public ContactLuo Xianghang
Xiangya Hospital Central South University
Outcome results
None listed