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Effects of Calcium Administration on Survival Rates in Patients with Sepsis

Effects of Parenteral Calcium Administration on 28-Day Mortality and Clinical Outcomes in Septic Patients with Hypocalcemia: A Bicenter Retrospective Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118246
Enrollment
Unknown
Registered
2026-02-03
Start date
2026-02-15
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

calcium-treated group :N/A
non-treated group:N/A

Sponsors

Southern Medical University Southern Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Consecutive patients admitted to the ICUs of two tertiary-grade-A hospitals between May 2022 and May 2024. 2.Age >= 18 years; 3.Meeting the Sepsis-3.0 diagnostic criteria; 4.ICU stay >= 48 hours with at least one documented ionized calcium (iCa) measurement; 5.Initial serum ionized calcium (iCa) < 1.15 mmol/L; 6.Only data from the first ICU admission during the same hospitalization were evaluated for patients readmitted during that stay.

Exclusion criteria

Exclusion criteria: 1.Patients receiving renal replacement therapy (RRT); 2.Patients with confirmed parathyroid dysfunction or bony metastasis from malignancy. 3.Death or ICU discharge occurring within 24 hours; 4.Incomplete calcium data or >20% missing values in key covariates;

Design outcomes

Primary

MeasureTime frame
28-day mortality;—

Countries

China

Contacts

Public ContactYanan Liu

Southern Medical University Southern Hospital

123302688@qq.com+86 20 6164 1049

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026