acute respiratory distress syndrome, ARDS
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children with moderate to severe ARDS (PaO2/FiO2 <= 200 mmHg) under mechanical ventilation; 2. Hypoxemia does not respond to other intervention measures; 3. Children aged 1 month to 16 years old.
Exclusion criteria
Exclusion criteria: 1. Severe skin lesions in the chest, 2. Chest surgery, 3. Chest trauma, 4. Severe arrhythmia, 5. Refractory shock, 6. Other situations that are not suitable for prone ventilation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of dorsal ventilation;Pulmonary ventilation-perfusion ratio;Percentage of ventral ventilation ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung dynamic compliance;Pulse oxygen saturation index;The duration of mechanical ventilation;PaO2/FiO2;Pulmonary static compliance;SpO2/FiO2;Center of ventilation;The global inhomogeneity index (GI);Oxygenation index;length of ICU stay; | — |
Countries
China
Contacts
Children's Hospital of Chongqing Medical University