Perinatal Depression
Conditions
Interventions
Treatment group:2-week rTMS treatment
Observation group:Blank Observation Period
Sponsors
Chengdu High-tech Zone Women and Children's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. According to the Structured Clinical Interview for DSM-V (SCID-I), diagnosed by a professional psychiatrist, it was confirmed as Major Depressive Disorder (MDD); 2. The first onset without any treatment; 3. Score of the Self-Rating Depression Scale (SDS) >= 53 points; 4. Score of the Edinburgh Postnatal Depression Scale (EPDS) >= 13; 5. Clinical Global Impression Severity Scale (CGI-S) >= 3; 6. Right-handed, with normal intelligence, vision and hearing. 7. Clear consciousness, able to understand the purpose of treatment, procedures and related risks.
Exclusion criteria
Exclusion criteria: 1. History of PTB; 2. Seizures in oneself or a first-degree relative; 3. There are metal or electronic devices in the brain (including cochlear implants, implanted brain stimulators or electrodes, aneurysm clips, etc.), cochlear implants, pacemakers, coronary stents, etc 4. Severe heart disease; 5. The fetus has known abnormalities; 6. Known obstetric complications include:; Hypertension during pregnancy or diabetes or abnormal prenatal examination; 7. History of drug or alcohol abuse in the past six months; 8. Lifetime diagnosis of mental illnesses other than MDD or anxiety disorders; 9. Previously, there was no response to electroconvulsive therapy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Near infrared functional imaging;EEG data; | — |
Countries
China
Contacts
Public ContactLiu Fang
Chengdu High-tech Zone Women and Children's Hospital/West China Second University Hospital of Sichuan University
Outcome results
None listed