Postoperative Delirium
Conditions
Interventions
Stellate Ganglion Block Group:Stellate Ganglion Block Group: Patients in this group will undergo two stellate ganglion block procedures: The first block will be performed the afternoon before the surg
the second will be administered 30 minutes before anesthesia induction on the day of the surgery. Under sterile conditions and real-time ultrasound guidance (at the C6 level), a 22-gauge needle will b
The sham group:2.Sham intervention (Control group)
An identical procedure will be performed at the corresponding time points (on the afternoon prior to surgery and 30 minutes before anesthesia induct
Sponsors
the Second Hospital & Clinical Medical School, Lanzhou University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years old; 2. Scheduled for elective open or laparoscopic radical gastrectomy or colorectal cancer surgery; 3. American Society of Anesthesiologists (ASA) physical status classification is grade I-III; 4. Able to provide a written informed consent (or through a legal representative).
Exclusion criteria
Exclusion criteria: 1. Previous cognitive impairment (MoCA score lower than the education-adjusted cutoff value) or diagnosed dementia; 2. Severe visual / auditory impairment or language disorder, making reliable delirium assessment impossible; 3. Severe mental illness (such as schizophrenia, bipolar disorder); 4.:local infection at the puncture site, known allergy to local anesthetics, severe coagulation dysfunction or inability to safely suspend therapeutic anticoagulation; 5. Severe systemic diseases: Child-Pugh C stage liver cirrhosis, end-stage renal disease (estimated glomerular filtration rate [eGFR] 6 hours; 7. History of substance abuse; 8. Pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Delirium severity score;Quality of recovery-15 ;Inflammatory biomarkers;Postop pain intensity;Opioid consumption;Postop complications; | — |
Countries
Chinese
Contacts
Public ContactYingbin Wang
The Second Hospital & Clinical Medical School, Lanzhou University
Outcome results
None listed