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Pulsed Radiofrequency at Different Voltages in the Treatment of zoster-associated neuralgia: A Multicenter Randomized Controlled Trial

Pulsed Radiofrequency at Different Voltages in the Treatment of zoster-associated neuralgia: A Multicenter Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118214
Enrollment
Unknown
Registered
2026-02-03
Start date
2026-02-03
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Zoster-associated Neuralgia

Interventions

Standard Voltage Group (Group S):The patient was placed in the prone position. The segments of the affected nerves were identified under C-arm or ultrasound guidance, with the dorsal root ganglia at t
High Voltage Group (Group H):The patient was placed in the prone position. The segments of the affected nerves were identified under C-arm or ultrasound guidance, with the dorsal root ganglia at the c

Sponsors

Shandong Provincial Hospital Affiliated to Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged 18 years or older, male or female; 2. Presenting with herpes zoster where the rash has resolved, experiencing moderate to severe pain (pain score >=4); 3. Possessing adequate comprehension to understand the treatment protocol and follow-up requirements; 4. Capable of accurate description, cooperative with treatment, and free from psychiatric disorders.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiac, cerebral, hepatic, or systemic diseases who cannot tolerate minimally invasive surgery; 2. Patients with concomitant infection at the puncture site, coagulation disorders, etc.; 3. Patients with other chronic pain conditions such as cancer pain; 4. Severe anatomical abnormalities preventing radiofrequency needle insertion into the target location; 5. Pregnancy or lactation; 6. Patients lacking the cognitive capacity to complete self-assessment scales within the trial.

Design outcomes

Primary

MeasureTime frame
Effective rate;

Secondary

MeasureTime frame
Short-form McGill Pain Questionnaire-2,SF-MPQ-2;Intraoperative sensory and motor testing parameters;Dose of Pregabalin;The Pittsburgh Sleep Quality Index,PSQI;the Hospital Anxiety and Depression Scale, HADS;12-Item Short Form Health Survey,SF-12;

Countries

China

Contacts

Public ContactSun Tao

Shandong Provincial Hospital Affiliated to Shandong First Medical University

suntaosdph@163.com+86 531 6877 8328

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026