Colorectal cancer
Conditions
Interventions
experimental group:Bilateral quadratus lumborum blocks were performed under ultrasound guidance before the induction of general anesthesia, with 20 mL of liposomal bupivacaine (133 mg diluted in norma
control group:Bilateral quadratus lumborum blocks were performed under ultrasound guidance before the induction of general anesthesia, with 20 mL of 0.375% ropivacaine administered on each side. Gener
Sponsors
Changzhou First People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 In line with the clinical diagnosis of primary colorectal cancer; 2 American Society of Anesthesiologists (ASA) Physical Status Classification Class I-III. 3 Meet the indications for radical resection of colorectal cancer and undergo laparoscopic radical resection of colorectal cancer; 4 Good cognitive function and basic communication skills; 5 Age >= 65 years old; 6 Patients and family members sign informed consent.
Exclusion criteria
Exclusion criteria: 1 Toxic shock, polytrauma, or adrenal insufficiency; 2 History of psychiatric disorders; 3 Severe hepatic or renal dysfunction such as liver fibrosis or uremia; 4 Coexisting other malignant tumors; 5 Coagulation abnormalities; 6 Previous history of abdominal surgery; 7 Infection at the puncture site; 8 Coexisting other gastrointestinal diseases; 9 History of allergy to the anesthetic agents used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of first anal exhaust after surgery;Time of first anal defecation after surgery;I-FEED score; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate;mean arterial pressure;Intraoperative blood loss;Postoperative recovery time;extubation time;duration of PACU stay;Numeric Rating Scale;PCA press count within 72 hours postoperatively;Total Opioid Consumption;Diamine Oxidase (DAO);D-lactate;Operation duration;Total postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactHu'ting'ting
Changzhou First People's Hospital
Outcome results
None listed