Lower extremity orthopedic surgery in elderly patients
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) ASA grades I~II (ASA: American Society of Anesthesiology); (2) Age >=65 years, voluntarily participating in this study and signing the informed consent form; (3) Surgery duration more than 1 hour; (4) Patients undergoing hip and lower limb orthopaedic surgery (hip surgery, lower limb surgery); (5) Patients able to communicate verbally and in writing; (6) No neurological diseases or brain function impairments; (7) Patients not recently taking neuropsychiatric medications and without alcohol abuse; (8) Patients without severe cardiovascular or pulmonary diseases.
Exclusion criteria
Exclusion criteria: (1) Severe liver and kidney dysfunction; (2) Patients who may be transferred to other departments (ICU, cardiology, respiratory, etc.) after surgery; (3) Patients with incomplete follow-up data.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Regional Cerebral Oxygen Saturation,rSO2;Mean Arterial Pressure, MAP;Heart Rate, HR; | — |
Primary
| Measure | Time frame |
|---|---|
| Neuron-Specific Enolase, NSE;Myelin Basic Protein, MBP;Cortisol;Adrenocorticotropic hormone; | — |
Countries
China
Contacts
3201 Hospital