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Analysis of High-Resolution Esophageal Manometry Characteristics and Endoscopic Comorbidities in Patients with Bitter Taste in the Mouth

Analysis of High-Resolution Esophageal Manometry Characteristics and Endoscopic Comorbidities in Patients with Bitter Taste in the Mouth

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118197
Enrollment
Unknown
Registered
2026-02-03
Start date
2026-02-03
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bitter taste

Interventions

control group:N/A
case group:N/A

Sponsors

Suining Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for the case group: 1. Age 18–70 years; 2. Persistent bitter taste in the mouth for more than 4 weeks, with gastroscopy ruling out organic lesions such as esophageal cancer; 3. Normal liver, gallbladder, and pancreas ultrasound and liver function tests; 4. Voluntarily signed informed consent. Inclusion criteria for the control group: 1. Age 18–80 years; 2. No gastrointestinal symptoms or diseases; 3. No other systemic or general diseases; 4. Voluntarily signed informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria for the case group: 1. Pregnant or breastfeeding women; 2. Use of medications that may affect upper gastrointestinal motility within the past 48 hours; 3. Presence of severe heart, lung, liver, or kidney dysfunction, or other diseases that make the examination intolerable; 4. Achalasia, eosinophilic esophagitis, or a history of upper gastrointestinal surgery. Exclusion criteria for the control group: 1.Pregnant or breastfeeding women; 2.Use of medications that may affect upper gastrointestinal motility within the past 48 hours.

Design outcomes

Primary

MeasureTime frame
Upper Esophageal Sphincter Pressure;Distal Contractile Integral;Lower Esophageal Sphincter Pressure;Upper Esophageal Sphincter Relaxation Rate;4-Second Integrated Relaxation Pressure;

Countries

China

Contacts

Public ContactZhang Xiumei

Suining Central Hospital

2652027489@qq.com+86 825 229 2610

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026