Stroke
Conditions
Interventions
Phrenic Nerve Electrical Stimulation Group:Phrenic nerve electrical stimulation: Using the Jinzhun medium-frequency therapy device (Registration No.: Min 20222090100) in diaphragmatic dysfunction mode
Conventional Rehabilitation Group:Conventional rehabilitation therapy, including position management, airway management, routine respiratory training, and limb function training.
Combined Treatment Group:Repetitive transcranial magnetic stimulation (rTMS): The patient is seated comfortably or in a semi-recumbent position. A Yiruide NS3000 magnetic stimulator is used, with the
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria of the Chinese Guidelines for the Management of Acute Ischemic Stroke or the Chinese Guidelines for the Management of Intracerebral Hemorrhage, and confirmed as intracerebral hemorrhage or cerebral infarction by cranial CT or MRI; 2. No restriction on gender, age 18–80 years; 3. Diaphragmatic ultrasound shows diaphragmatic thickening fraction <20% or end-expiratory diaphragmatic thickness <0.2 cm; 4. The participant personally signs the "Informed Consent Form"; if unable to sign, a witness may sign on their behalf under video recording after obtaining verbal consent; 5. Confirmed by the investigator to have no major chronic diseases or acute infectious diseases; vital signs stable with no obvious contraindications; 6. Consciousness requirement: patient is alert and able to cooperate with high-compliance examinations such as pulmonary function tests; patients in coma or otherwise unable to cooperate are excluded; 7. No cognitive impairment.
Exclusion criteria
Exclusion criteria: 1. History of pulmonary, thoracic, or abdominal diseases, or other conditions affecting respiratory function, such as chronic obstructive pulmonary disease (COPD), asthma, or pulmonary fibrosis; 2. History of smoking; 3. Neuromuscular diseases: myasthenia gravis or other neuromuscular disorders that may affect respiratory function, such as motor neuron disease, polymyositis, or muscular dystrophy; 4. Concurrent severe cardiovascular disease, cirrhosis, renal failure, serious systemic illness, or history of malignancy; 5. Presence of metallic implants in the body; 6. History of epilepsy; 7. Severe cognitive impairment or severe facial paralysis: patients unable to cooperate with examinations due to severe cognitive impairment or severe facial paralysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragmatic Thickening Fraction (DTF);Diaphragm Displacement;Fugl-Meyer Assessment (FMA);Apnea-Hypopnea Index (AHI); | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary Function;Nocturnal Hypoxia Severity;Diaphragmatic Electromyography (dEMG); | — |
Countries
China
Contacts
Public ContactWu Junfa
Huashan Hospital, Fudan University
Outcome results
None listed