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Central venous administration of fospropofol reduces paresthesia: A randomized controlled trial

Central venous administration of fospropofol reduces paresthesia: A randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118173
Enrollment
Unknown
Registered
2026-02-03
Start date
2026-02-03
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Peripheral vein group:Intravenously administered with fospropofol through the peripheral vein.
Central venous group:Intravenously administered with fospropofol through the central vein.

Sponsors

The Third People's Hospital of Yibin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1)Patients scheduled for elective surgeries who require deep vein catheterization due to their medical conditions. (2)ASA I-III. (3)18 to 65 years old.

Exclusion criteria

Exclusion criteria: (1)The patient refused. (2)The patients who with contraindications for deep vein puncture, such as infection or burn at the puncture site, known thrombosis of the puncture vessel, occlusion of the puncture vessel, coagulation dysfunction, abnormal or variant anatomical structure, or when the patient is unable to cooperate. (3)Patients who are allergic to fospropofol. (4)Patients with skin diseases and abnormal skin sensations. (5)Patients with severe liver and kidney dysfunction. (6)Patients who participated in other interventional studies within three months.

Design outcomes

Primary

MeasureTime frame
The incidence rate of abnormal sensations;

Secondary

MeasureTime frame
The onset time of sedative effect;The incidence of hypotension;The degree of decrease in the lowest blood pressure (mean arterial pressure, MAP) during anesthesia induction;

Countries

China

Contacts

Public ContactLi Xiong

The Third People's Hospital of Yibin

18606108@qq.com+86 831 822 6382

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026