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Comparative Study of Prefrontal Electroencephalographic Features During Deep Sedation With Remimazolam Versus Propofol in Young and Middle-Aged Patients

Comparative Study of Prefrontal Electroencephalographic Features During Deep Sedation With Remimazolam Versus Propofol in Young and Middle-Aged Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118168
Enrollment
Unknown
Registered
2026-02-03
Start date
2026-02-05
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

none

Interventions

Propofol group:Propofol
Remimazolam group:Remimazolam

Sponsors

The Second Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Age 18–64 years; 2. ASA classification I–II; 3. BMI 18–28 kg/m^2; 4. Patients scheduled for elective surgery under general anesthesia; 5. Voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Allergy to benzodiazepines; 2. Difficult airway assessed by an anesthesiologist; 3. Previous diagnosis of coronary heart disease or other cardiovascular and pulmonary dysfunction; 4. Diagnosed with mental disorders such as depression, anxiety, schizophrenia, or abuse of medications or alcohol; 5. Significant abnormalities in liver and kidney function laboratory test results; 6. Structural abnormalities of the heart or lungs found in imaging examinations; 7. Patients who refuse to participate in this study.

Design outcomes

Primary

MeasureTime frame
Alpha-band spectral power;

Secondary

MeasureTime frame
Delta-band spectral power;PSI values at different time points;Alpha-band coherence;Collected using the SedLine EEG monitoring system;

Countries

China

Contacts

Public ContactHaiding Zou

The Second Xiangya Hospital, Central South University

zhd2019@csu.edu.cn+86 150 8496 8406

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026