Stroke
Conditions
Interventions
cM1 group:Intervention of the cM1 by ITBS
False Stimulus Group:Intervention of the cM1 by false ITBS
cPMd group:Intervention of the cPMd by ITBS
Sponsors
Shanghai Second Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.The diagnosis conforms to the "Key Points for Diagnosis of Major Cerebrovascular Diseases in China 2019" standards and is confirmed by head CT or MRI; 2.First occurrence of unilateral cerebral hemisphere infarction/hemorrhage, and the patient with hemorrhage has never undergone head surgery; 3.Age is 55-85 years old; 4.Disease course is 3-12 months; 5.Moderate to severe motor function impairment exists, with the proximal part of the FMA-UE score on the hemiplegic side < 26 points, and poor response to conventional neuroregulation; 6.The patient or their immediate family members understand and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Patients with unstable conditions and vital signs; 2.Patients who cannot tolerate iTBS treatment; 3.Patients with a history of Parkinson's disease, peripheral neuropathy, and other conditions that can cause motor dysfunction; 4.Patients with concurrent tumors, severe respiratory, cardiac, hepatic, renal, endocrine and hematopoietic system diseases, etc; 5.Pregnant and lactating women; 6.Patients with a history of epilepsy or a family history of epilepsy, those with metal pacemakers in the body, metal implants in the brain, cochlear implants, and skull defects, etc., who are not suitable for transcranial magnetic stimulation treatment; 7.Patients currently participating in other clinical trials or those who have recently received neuromodulation treatment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Near Infrared (fNIRS) Detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment-Upper Extremity; | — |
Countries
China
Contacts
Public ContactCheng Xie
Shanghai Second Rehabilitation Hospital
Outcome results
None listed