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The Effect of Tejilidine Combined with Transversus Abdominis Plane Block on Postoperative Patient-Controlled Analgesia in Patients Undergoing Laparoscopic Total Hysterectomy

The Effect of Tejilidine Combined with Transversus Abdominis Plane Block on Postoperative Patient-Controlled Analgesia in Patients Undergoing Laparoscopic Total Hysterectomy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118132
Enrollment
Unknown
Registered
2026-02-02
Start date
2026-02-02
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine fibroids, cervical cancer

Interventions

butorphanol group (Group B):butorphanol
Tegileridine group (Group T):Tegileridine

Sponsors

Jinan Maternal and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.ASA physical status I–III; 2.Aged 18–65 years; 3.BMI 18–30 kg/m²; 4.Willing to participate voluntarily in this study; 5.No severe cardiac or pulmonary disease;

Exclusion criteria

Exclusion criteria: 1.Chronic pain; 2.History of psychiatric disorders; 3.History of long-term opioid use; 4.Patients with acute or severe bronchial asthma; 5.Patients with known hypersensitivity to opioids. 6.Patients with severe hepatic or renal insufficiency; 7.Patients with acute intestinal obstruction; 8.Patients with acute intestinal perforation; 9.Long-term use of anxiolytics, antipsychotics, or antidepressants;

Design outcomes

Primary

MeasureTime frame
Record resting NRS scores;

Secondary

MeasureTime frame
Time to first rescue analgesi;Record resting and dynamic NRS scores;Incidence of adverse events (pruritus, respiratory depression, nausea, vomiting, urinary retention);QoR-15 (15-item Quality of Recovery Scale), Ramsay Sedation Score, and sleep-quality satisfaction score ;

Countries

China

Contacts

Public ContactYanan Liang

Jinan Maternal and Child Health Care Hospital

398287069@qq.com+86 531 8176 9618

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026