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Mechanism and prediction model construction of differences in stroke rehabilitation efficacy based on multimodal biomarkers: a prospective cohort study of stroke whole course management

Mechanism and prediction model construction of differences in stroke rehabilitation efficacy based on multimodal biomarkers: a prospective cohort study of stroke whole course management

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118129
Enrollment
Unknown
Registered
2026-02-02
Start date
2026-02-02
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Rehabilitation unresponsive group:None
Rehabilitation responders:None

Sponsors

Shanghai Tongren Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age>= 18 years old; 2.First clinical diagnosis of acute ischemic or hemorrhagic stroke (confirmed by CT/MRI); 3.Admitted within 48 hours after onset of illness; 4.There are clear neurological deficits (such as limb movement, speech, and sensory disorders); 5.Vital signs are stable and can tolerate early rehabilitation after evaluation; 6.The patient or their legal representative signs an informed consent form;

Exclusion criteria

Exclusion criteria: 1.History of significant or disabling stroke in the past; 2.Combining severe cognitive impairment (MMSE<10 points) or mental illness, unable to cooperate with assessment and rehabilitation; 3.Combining diseases such as severe heart, liver, kidney failure or tumors that affect survival; 4.There are contraindications for MRI or TMS examination (such as metal implants, pacemakers, history of epilepsy, etc.); 5.It is expected that a 6-month follow-up cannot be completed;

Design outcomes

Primary

MeasureTime frame
Modified Rankin Scale (mRS) score;

Secondary

MeasureTime frame
Fugl Meyer Motor Function;Barthel Index (BI);Stroke Specific Quality of Life (SS-QOL);Modified Rankin Scale (mRS) score;

Countries

China

Contacts

Public ContactXueyuan Liu

Shanghai Tongren Hospital

lxyshtj@163.com+86 21 6630 1161

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026