Persistent Post-surgical Pain (PPSP)
Conditions
Interventions
Control group:After fetal delivery, the parturient received an intravenous infusion of 20 mL of normal saline over a duration of 20 minutes. Postoperatively, the patient was administered patient-contr
S-ketamine group:After fetal delivery, the parturient received an intravenous infusion of 20 mL of S-ketamine 0.25mg/kg over a duration of 20 minutes. Postoperatively, the patient was administered pat
Sponsors
Women' Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Preoperative anxiety (GAD-7 score >= 7); (2) Age 20-45 years; (3) Women with scarred uterus; (4) Body Mass Index <= 40 kg/m^2; (5) undergo repeat cesarean section.
Exclusion criteria
Exclusion criteria: (1) Patients who have used opioids or other sedative analgesics within one week; (2) Patients allergic to the active ingredient or any excipients of this product; (3) Patients at serious risk of elevated blood pressure or intracranial pressure; (4) Pregnant women with preeclampsia or eclampsia. (5) Patients with severe cardiac, pulmonary, hepatic, or renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PPSP ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores;Effective pain relief rate;The consumption of opioid drugs;Recovery quality assessment;Postpartum depress assessment;Maternal and neonatal bonding assessment; | — |
Countries
China
Contacts
Public ContactXia Fan
Women' Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital
Outcome results
None listed