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Impact of continuous pecto-intercostal fascial block on postoperative fatigue in elderly patients undergoing cardiac surgery via median sternotomy: a randomized controlled trial

Impact of continuous pecto-intercostal fascial block on postoperative fatigue in elderly patients undergoing cardiac surgery via median sternotomy: a randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118123
Enrollment
Unknown
Registered
2026-02-02
Start date
2026-02-02
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative fatigue syndrome

Interventions

single pecto-intercostal fascial block group(S-PIFB group):To be completed within 20 minutes before anesthesia induction in the operating room, a single ultrasound-guided PIFB (20 ml of 0.4% ropivacai
continuous pecto-intercostal fascial block group(C-PIFB group):The procedure for bilateral single-shot nerve blocks under ultrasound guidance is the same as that for S-PIFB group. Subsequently, a cat

Sponsors

The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Study participants scheduled for elective off-pump cardiac surgery via median sternotomy; 2. Aged >=60 years; 3. American Society of Anesthesiologists health status 2 to 3.

Exclusion criteria

Exclusion criteria: 1. Body mass index (BMI)> 30 kg/m²; 2. A preoperative diagnosis of fatigue syndrome (visual analog scale score > 5); 3. Allergy to local anesthetics; 4. History of psychiatric or psychological diseases; 5. History of chronic pain; 6. Preoperative use of nonsteroidal anti-inflammatory drugs (NSAIDs) or opioid analgesics; 7. Preoperative severe hepatic or renal dysfunction; 8. Congestive heart failure.

Design outcomes

Primary

MeasureTime frame
the incidence of postoperative fatigue syndrome within 8 postoperative weeks;

Secondary

MeasureTime frame
the incidence of postoperative fatigue syndrome within 7 postoperative days;Duration of postoperative fatigue syndrome;the postoperative pain;postoperative opioid consumption;extubation time;duration of ICU stay;Quality of recovery postoperatively;length of hospital stay;Incidence of adverse events;the score of the ICFS-10 scale;

Countries

China

Contacts

Public ContactSu Liu

The Affiliated Hospital of Xuzhou Medical University

liusu_xzmu@163.com+86 181 1830 9692

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026