Neurocognitive function
Conditions
Interventions
Group T:The electric stimulator was placed in the bilateral ear nail boat area. Parameters: frequency 20Hz, pulse width 300 µ s, intensity limited to the patients tolerance (current intensity about 0.
Group C:Sham stimulation (the appearance of the device is the same, the electrode is attached to the non vagus nerve distribution area of the earlobe, and there is no current output)
Sponsors
Lishui People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: The age should be > = 65 years old and < = 90 years old (no limit for men and women); American Society of anesthesiologists (ASA) physical status class I-III; Elective surgery to be performed under general anesthesia; Preoperative frailty assessment met frail frailty assessment scale = 3 points; It can be treated with auricular acupoint electrical stimulation; Signed informed consent.
Exclusion criteria
Exclusion criteria: Severe hearing impairment or ear skin damage; Previous vagus nerve injury or pacemaker implantation; Preoperative Montreal Cognitive Assessment Scale (MoCA) < 27 points (education <= 12 years, plus 1 point); With severe mental disease or neurodegenerative disease (such as Alzheimer's disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of POD; | — |
Secondary
| Measure | Time frame |
|---|---|
| the incidence of DNR;the incidence of p-NCD;Inflammatory markers: serum tnf- a, IL-6, IL-1 ß were detected;Brain injury markers: detection of serum s100- ß, NSE;Postoperative recovery quality (qor-15);Vital signs (map, HR) at different time points;Adverse reactions during tavns treatment: dizziness and headache, local skin reaction, ear pain, nausea;Incidence of intraoperative adverse events: hypotension, bradycardia, hypertension, tachycardia; | — |
Countries
China
Contacts
Public ContactDuan Gongchen
Lishui People's Hospital
Outcome results
None listed