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Construction and Validation of a Radiotherapy Efficacy Prediction Model for Cervical Cancer Based on Domestically Developed Equipment Integrating Multimodal Radiomics and Molecular Mechanisms

Construction and Validation of a Radiotherapy Efficacy Prediction Model for Cervical Cancer Based on Domestically Developed Equipment Integrating Multimodal Radiomics and Molecular Mechanisms

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118095
Enrollment
Unknown
Registered
2026-02-02
Start date
2025-10-27
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical cancer

Interventions

Observation group:None

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years and = 3×10^9/L, NEUT >= 1.5×10^9/L, PLT >= 100×10^9/L, Hb >= 90 g/L ; Liver function: TBIL = 60 ml/min.

Exclusion criteria

Exclusion criteria: 1.Previous surgical treatment for cervical cancer; 2.History of pelvic radiotherapy; 3.History of other malignant tumors; 4.Pregnant or breastfeeding women; 5.Presence of active infection or fever; 6.Severe underlying diseases or poor general condition that precludes completion of treatment or follow-up; 7.Insufficient tissue sample quantity or inadequate RNA quality for transcriptome sequencing; 8.Refusal to undergo tissue sampling or failure to provide written informed consent.

Design outcomes

Primary

MeasureTime frame
12-month DFS;—

Secondary

MeasureTime frame
Tumor volume reduction rate;Disease control rate (DCR);Objective response rate (ORR);—

Countries

China

Contacts

Public ContactXiaorong Hou

Peking Union Medical College Hospital

hxr_pumch@163.com+86 10 69155485

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026