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Esophageal Pressure-guided Personalized Recruitment Pressure during Pneumoperitoneum in Trendelenburg Position Laparoscopy: A Prospective Randomized Controlled Trial

Esophageal Pressure-guided Personalized Recruitment Pressure during Pneumoperitoneum in Trendelenburg Position Laparoscopy: A Prospective Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118077
Enrollment
Unknown
Registered
2026-02-02
Start date
2026-02-20
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Personalized Lung Recruitment Pressure Group:A transnasally placed esophageal balloon catheter was inserted. Following a positive-pressure occlusion test, end-inspiratory and end-expiratory esophageal
Fixed Lung Recruitment Pressure Group:A single-cycle lung recruitment maneuver was performed at a fixed pressure of 30 cmH?O for 10 seconds, both 30 minutes after pneumoperitoneum establishmentand imm

Sponsors

North Jiangsu People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age of 18-65 years old, both sexes; 2. ASA I-III; 3. BMI24-30 4. No recent history of pulmonary infection or disease, and no history of respiratory system related surgery;

Exclusion criteria

Exclusion criteria: 1. BMI30; 2. Chronic obstructive pulmonary disease or cor pulmonale; 3. Chronic diseases such as uncontrolled diabetes and hypertension; 4. Abnormal cardiac function; 5. Recent use of non-steroidal anti-inflammatory drugs or hormone drugs; 6. Esophageal lesions (esophageal manometry balloon is contraindicated); 7. History of esophageal surgery; 8. Indications for recruitment maneuvers: intracranial hypertension, hypovolemic shock, right heart failure;

Design outcomes

Primary

MeasureTime frame
Lung Compliance;Rate of non?surgical antibiotic use;Length of stay in the PACU after extubation;

Secondary

MeasureTime frame
Driving Pressure;Modified LUS Score;The incidence of PPCs on postoperative day 3.;

Countries

China

Contacts

Public ContactGao Ju

North Jiangsu People's Hospital

doctor2227@163.com+86 180 5106 3988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026