Allergic rhinitis
Conditions
Interventions
Control group:Standard treatment
Experimental group:Standard treatment + Exosome nebulization
Sponsors
The First Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.meets the diagnostic criteria for allergic rhinitis in 'Otorhinolaryngology-Head and Neck Surgery'; 2.accompanied by symptoms such as itchy nose, nasal congestion, and runny nose; 3.has not received any medication treatment within the past month; 4.no severe dysfunction of major organs; 5.no other nasal diseases or immune system disorders; 6.no consciousness or psychiatric disorders; 7.no allergy or contraindication to the study drug; 8.patient or family is informed about this study and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women. 2. Patients who cannot clearly state the history, have difficulty communicating, or are unwilling to cooperate with the examination. 3. Patients with chronic sinusitis, bronchial asthma, nasal tumors, acute onset of allergic rhinitis, allergic pharyngitis, secretory otitis media, acute rhinitis, hyperrefletic rhinitis, non-allergic rhinitis with gel hyperalgesia syndrome, vasomotor rhinitis and other nasal diseases with nasal manifestations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eosinophil and ECP testing;Total TNSS nasal symptom score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The RQLQ scale;ELISA detection of immune markers;Pulmonary function assessment;Flow cytometry detection of T cell subsets; | — |
Countries
China
Contacts
Public ContactZhang Aichun
The First Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed