Interstitial Pneumonia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adults aged >=18 years with a clinical suspicion of interstitial lung disease (ILD) requiring diagnostic evaluation. 2.Chest high-resolution computed tomography (HRCT) findings classified as either a "Possible UIP" or "Indeterminate for UIP" pattern according to the 2022 ATS/ERS/JRS/ALAT guidelines. 3.Cases where the multidisciplinary team (MDT) determines that a definitive diagnosis cannot be reached without further investigation, thereby warranting consideration for lung biopsy. 4.Ability to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1.Pre-existing, histopathologically confirmed diagnosis of ILD. 2. Lung biopsy (transbronchial or surgical) performed within 30 days prior to enrollment. 3. Contraindications to MRI, including but not limited to incompatible pacemakers, metallic implants, or severe claustrophobia. 4. Presence of severe comorbidities that, in the judgment of the investigator, would confer an unacceptably high risk for anesthesia or lung biopsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion undergoing invasive lung biopsy within 90 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to reach a definitive diagnosis; | — |
Countries
China
Contacts
Guilin Medical University Affiliated Hospital