Osteonecrosis of the Femoral Head
Conditions
Interventions
Experimental group:In the self-curing calcium phosphate artificial bone, two injections of autologous vascular matrix components were performed according to the established protocol.
Control group:Only one SVF injection was performed during the surgery, with the injection dose, cell concentration, and localization method consistent with the experimental group.
Sponsors
Chinese People's Liberation Army General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age 18–60 years; 2.Diagnosed with femoral head necrosis, radiological staging ARCO I–IIIA; 3.Planned for core decompression + calcium phosphate bone cement filling to preserve the hip; 4.Consent to accept SVF preparation and injection (single or multiple sessions); 5.Sign informed consent form.
Exclusion criteria
Exclusion criteria: 1History of previous hip joint replacement or major surgery on the same side; 2.Active infection or infection at the injection/surgical site; 3.Severe coagulation dysfunction or inability to discontinue anticoagulation/antiplatelet drugs and not suitable for puncture; 4.Severe heart, liver, renal dysfunction or unable to tolerate surgery; 5.Malignant tumor, pregnancy/lactation; 6.Other conditions deemed unsuitable for enrollment by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 12-month incidence of THA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of hip joint function;Assessment of pain degree;Gait analysis;Appraisal of life quality; | — |
Countries
China
Contacts
Public ContactPeng Jiang
Chinese People's Liberation Army General Hospital
Outcome results
None listed