Deformitiesofteethandmandible, postoperative nausea and vomiting
Conditions
Interventions
Ondansetron group (group A):Ondansetron (IV)
Ondansetron + Metoclopramide group (group B):Ondansetron + Metoclopramide (IV)
Sponsors
Beijing Stomatological Hospital , Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1.Ages 18-35, gender not restricted; 2.ASA GRADE I-II; 3.Cardiopulmonary function and other vital organ functions are essentially normal, and the patient can tolerate anesthesia and surgery;
Exclusion criteria
Exclusion criteria: 1.Obese patients with a BMI greater than 30; 2.Patients with apnea syndrome, suspected mask ventilation difficulty, and tracheal intubation difficulty; 3.Patients prone to nausea and vomiting due to motion sickness and vestibular dysfunction; 4.Patients with mental disorders such as depression and anxiety; 5.Patients with a history of epilepsy; 6.Patients with drug allergies to the medications used in the study protocol; 7.Pregnant and lactating women; 8.Patients with intellectual disabilities;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of nausea and vomiting within 48 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean intraoperative arterial pressure of the patient;Numbers of trigeminal-vagal reflexes during surgery;Blood loss of the patient at the intraoperative period;Pain scores at 24 hours and 48 hours postoperative period; | — |
Countries
China
Contacts
Public ContactLiu Yurui
Beijing Stomatological Hospital , Capital Medical University
Outcome results
None listed