Skip to content

LIBS-Based Correlation Study of Serum and Tissue Biomarkers in Pituitary Neuroendocrine Tumors (PitNETs)

LIBS-Based Correlation Study of Serum and Tissue Biomarkers in Pituitary Neuroendocrine Tumors (PitNETs)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118035
Enrollment
Unknown
Registered
2026-02-01
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pituitary neuroendocrine tumor

Interventions

Case group:None
Control group:None

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with PitNETs: 1. Age >= 18 years old. 2. Diagnosed with PitNETs through imaging (MRI) and pathological examinations. 3. Include both functional (such as prolactinoma, GH tumor) and non-functional subtypes. 2. Healthy controls: 1. Age >= 18 years old. 2. No history of endocrine diseases or tumor-related diseases. 3. All participants: Must sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Suffering from severe dysfunction of heart, liver, kidney or other serious systemic diseases; 2. Having mental disorders or cognitive problems and being unable to cooperate with the research; 3. Planning to move out of the local area or unable to complete the follow-up; 4. Other situations judged by the researchers as not suitable for participating in this study (such as poor compliance); 5. Specifically regarding sample quality: In the research, to ensure the accuracy of LIBS detection, samples with unreliable data due to sample preparation problems (such as severe hemolysis, tissue autolysis) need to be excluded;

Design outcomes

Primary

MeasureTime frame
Model classification accuracy rate;Sensitivity;Specificity;Area under the receiver operating characteristic curve;

Secondary

MeasureTime frame
Strength of key element spectral lines;The correlation between elemental spectra and clinical parameters;

Countries

China

Contacts

Public ContactXiao Wu

The First Affiliated Hospital of Nanchang University

wuxiaosjwk@163.com+86 7551234567

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026