Pituitary neuroendocrine tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with PitNETs: 1. Age >= 18 years old. 2. Diagnosed with PitNETs through imaging (MRI) and pathological examinations. 3. Include both functional (such as prolactinoma, GH tumor) and non-functional subtypes. 2. Healthy controls: 1. Age >= 18 years old. 2. No history of endocrine diseases or tumor-related diseases. 3. All participants: Must sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffering from severe dysfunction of heart, liver, kidney or other serious systemic diseases; 2. Having mental disorders or cognitive problems and being unable to cooperate with the research; 3. Planning to move out of the local area or unable to complete the follow-up; 4. Other situations judged by the researchers as not suitable for participating in this study (such as poor compliance); 5. Specifically regarding sample quality: In the research, to ensure the accuracy of LIBS detection, samples with unreliable data due to sample preparation problems (such as severe hemolysis, tissue autolysis) need to be excluded;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Model classification accuracy rate;Sensitivity;Specificity;Area under the receiver operating characteristic curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Strength of key element spectral lines;The correlation between elemental spectra and clinical parameters; | — |
Countries
China
Contacts
The First Affiliated Hospital of Nanchang University