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Comparison of the Application of Oliceridine or Sufentanil Combined with Propofol in Painless Gastroscopy Anesthesia

Comparison of the Application of Oliceridine or Sufentanil Combined with Propofol in Painless Gastroscopy Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118032
Enrollment
Unknown
Registered
2026-02-01
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painless gastroscopy

Interventions

Trial group:Sufentanil at a dose of 0.1 µg/kg was intravenously injected, followed by intravenous induction of propofol at a dose of 2 mg/kg. During the operation, propofol was pumped at a dose of 2-4
Control group:Oxelidine was intravenously injected at a dose of 0.02 mg/kg, followed by intravenous induction of propofol at a dose of 2 mg/kg. During the operation, propofol was pumped at a dose of 2

Sponsors

Guangzhou Women and Children's Medical Center Liuzhou Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients who underwent painless gastroscopy at Liuzhou Hospital of Guangzhou Women and Children's Medical Center and voluntarily participated in the study and signed the informed consent form; 2. aged >=18 and <=60 years; 3. BMI 18-28 kg/m^2; 4. ASA classification I or II

Exclusion criteria

Exclusion criteria: 1. Those who have had cognitive dysfunction, suffer from mental disorders, and have communication and interaction difficulties; 2. Those with a history of alcohol or drug abuse; 3. Those who used anesthetic drugs, sedatives, or opioid drugs within 24 hours before the surgery; 4. Those who participated as subjects in any clinical trial within the previous 3 months; 5. Those who are allergic or hypersensitive to the drugs used in this study; 6. Pregnant or lactating women or those with a fertility plan within 3 months; 7. Those with symptoms of acute upper gastrointestinal bleeding or those requiring endoscopic examination and treatment; 8. Those who need complex endoscopic techniques for diagnosis and treatment; 9. Those who plan to undergo tracheal intubation; 10. Those who are judged to have difficult respiratory management.

Design outcomes

Primary

MeasureTime frame
The incidence of intraoperative respiratory depression;

Secondary

MeasureTime frame
Blood pressure change;heart rate variation;Drug dosage;Awakening time;The sedation level of the patient every 5 minutes within 20 minutes after drug withdrawal;

Countries

China

Contacts

Public ContactOu Lianchun

Guangzhou Women and Children's Medical Center Liuzhou Hospital

olianchun6688@163.com+86 133 6762 8675

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026