incidence of postoperative nausea and vomiting after cholecystectomy
Conditions
Interventions
ciprofol:Induction: Ciprofol 0.4 mg/kg + sufentanil 0.3–0.5 µg/kg + rocuronium bromide 0.6 mg/kg.
Maintenance: Anesthesia was maintained with ciprofol, remimazolam and rocuronium bromide, and the bisp
Remimazolam:Induction: Remimazolam 12 mg/kg/h + sufentanil 0.3–0.5 µg/kg + rocuronium bromide 0.6 mg/kg.
Maintenance: Anesthesia was maintained with remimazolam, remifentanil and rocuronium bromide, a
Sponsors
Wuxi Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18–70 years old, regardless of gender 2.ASA physical status classification: Grade ?–? 3.Type of surgery: Patients scheduled for elective laparoscopic cholecystectomy 4.Informed consent: Voluntarily sign the informed consent form
Exclusion criteria
Exclusion criteria: 2.Including pregnancy or lactation period, history of drug allergy, previous postoperative nausea and vomiting (PONV) score >= 3, preoperative use of opioids, severe cardiopulmonary dysfunction, or intolerance to general anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PONV;Severe Nausea Rating;Rescue antiemetic usage ratio and dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of regaining consciousness and extubation; | — |
Countries
China
Contacts
Public ContactDongxiao Huang
Wuxi Second People's Hospita
Outcome results
None listed